BDBM50114342 (E)-2-(dimethylamino)-N'-((S)-2-((S)-2-(4-fluorophenylsulfonamido)-3-methylbutanamido)-4-methylpentylidene)acetohydrazide::(S)-N-{(S)-1-[(2-Dimethylamino-acetyl)-hydrazonomethyl]-3-methyl-butyl}-2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyramide::CHEMBL288882

SMILES: CC(C)C[C@H](NC(=O)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(C)C)C=NNC(=O)CN(C)C

InChI Key: InChIKey=WUINYGBPWKNVAB-PXNSSMCTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50114342 ((E)-2-(dimethylamino)-N'-((S)-2-((S)-2-(4-fluoroph...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(C)C)C=NNC(=O)CN(C)C |w:24.25| Show InChI InChI=1S/C21H34FN5O4S/c1-14(2)11-17(12-23-25-19(28)13-27(5)6)24-21(29)20(15(3)4)26-32(30,31)18-9-7-16(22)8-10-18/h7-10,12,14-15,17,20,26H,11,13H2,1-6H3,(H,24,29)(H,25,28)/t17-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of human erythrocyte mu calpain				J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48
					More data for this Ligand-Target Pair
Calpain-1 (Sus scrofa (pig))	BDBM50114342 ((E)-2-(dimethylamino)-N'-((S)-2-((S)-2-(4-fluoroph...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(C)C)C=NNC(=O)CN(C)C |w:24.25| Show InChI InChI=1S/C21H34FN5O4S/c1-14(2)11-17(12-23-25-19(28)13-27(5)6)24-21(29)20(15(3)4)26-32(30,31)18-9-7-16(22)8-10-18/h7-10,12,14-15,17,20,26H,11,13H2,1-6H3,(H,24,29)(H,25,28)/t17-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Senju Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Tested for inhibitory activity against porcine erythrocyte Mu-calpain				Bioorg Med Chem Lett 12: 1603-6 (2002) BindingDB Entry DOI: 10.7270/Q20K27WS
					More data for this Ligand-Target Pair