BDBM50118479 2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyric acid::CHEMBL334842

SMILES: N[C@H](CCc1ns[nH]c1=O)C(O)=O

InChI Key: InChIKey=AJASJCCJLLTPOF-GSVOUGTGSA-N

Data: 1 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50118479 (2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...) Show SMILES N[C@H](CCc1ns[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H9N3O3S/c7-3(6(11)12)1-2-4-5(10)9-13-8-4/h3H,1-2,7H2,(H,9,10)(H,11,12)/t3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1				J Med Chem 45: 4240-5 (2002) BindingDB Entry DOI: 10.7270/Q28G8K2W
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50118479 (2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...) Show SMILES N[C@H](CCc1ns[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H9N3O3S/c7-3(6(11)12)1-2-4-5(10)9-13-8-4/h3H,1-2,7H2,(H,9,10)(H,11,12)/t3-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5				J Med Chem 45: 4240-5 (2002) BindingDB Entry DOI: 10.7270/Q28G8K2W
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50118479 (2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...) Show SMILES N[C@H](CCc1ns[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H9N3O3S/c7-3(6(11)12)1-2-4-5(10)9-13-8-4/h3H,1-2,7H2,(H,9,10)(H,11,12)/t3-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2				J Med Chem 45: 4240-5 (2002) BindingDB Entry DOI: 10.7270/Q28G8K2W
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM50118479 (2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...) Show SMILES N[C@H](CCc1ns[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H9N3O3S/c7-3(6(11)12)1-2-4-5(10)9-13-8-4/h3H,1-2,7H2,(H,9,10)(H,11,12)/t3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4				J Med Chem 45: 4240-5 (2002) BindingDB Entry DOI: 10.7270/Q28G8K2W
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor associated protein 1 (Rattus norvegicus)	BDBM50118479 (2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...) Show SMILES N[C@H](CCc1ns[nH]c1=O)C(O)=O Show InChI InChI=1S/C6H9N3O3S/c7-3(6(11)12)1-2-4-5(10)9-13-8-4/h3H,1-2,7H2,(H,9,10)(H,11,12)/t3-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.87E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Binding affinity towards N-methyl-D-aspartate glutamate receptor (NMDA) determined electrophysically using the rat cortical wedge model.				J Med Chem 45: 4240-5 (2002) BindingDB Entry DOI: 10.7270/Q28G8K2W
					More data for this Ligand-Target Pair