BDBM50118504 1-(4-Benzyloxy-but-2-enyl)-5-methyl-1H-pyrimidine-2,4-dione::CHEMBL132921

SMILES: Cc1cn(C\C=C/COCc2ccccc2)c(=O)[nH]c1=O

InChI Key: InChIKey=UWVHGIHVWKAXQU-WAYWQWQTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM50118504 (1-(4-Benzyloxy-but-2-enyl)-5-methyl-1H-pyrimidine-...) Show SMILES Cc1cn(C\C=C/COCc2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C16H18N2O3/c1-13-11-18(16(20)17-15(13)19)9-5-6-10-21-12-14-7-3-2-4-8-14/h2-8,11H,9-10,12H2,1H3,(H,17,19,20)/b6-5-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibitory effect against phosphorylation of [methyl-3H]dThd by Thymidine Kinase 2 (TK-2)				J Med Chem 45: 4254-63 (2002) BindingDB Entry DOI: 10.7270/Q2GQ6ZGB
					More data for this Ligand-Target Pair