BDBM50120685 2-[3-(4-Allyloxy-phenyl)-3-methyl-2-oxo-pyrrolidin-1-yl]-N-hydroxy-propionamide::CHEMBL359424

SMILES: C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCC=C)cc1)C(=O)NO

InChI Key: InChIKey=MJJPSHCMTYJCDM-PXAZEXFGSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50120685 (2-[3-(4-Allyloxy-phenyl)-3-methyl-2-oxo-pyrrolidin...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCC=C)cc1)C(=O)NO Show InChI InChI=1S/C17H22N2O4/c1-4-11-23-14-7-5-13(6-8-14)17(3)9-10-19(16(17)21)12(2)15(20)18-22/h4-8,12,22H,1,9-11H2,2-3H3,(H,18,20)/t12-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity towards Matrix metalloprotease-9 (MMP-9)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50120685 (2-[3-(4-Allyloxy-phenyl)-3-methyl-2-oxo-pyrrolidin...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCC=C)cc1)C(=O)NO Show InChI InChI=1S/C17H22N2O4/c1-4-11-23-14-7-5-13(6-8-14)17(3)9-10-19(16(17)21)12(2)15(20)18-22/h4-8,12,22H,1,9-11H2,2-3H3,(H,18,20)/t12-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity for Matrix metalloprotease-2 (MMP-2)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50120685 (2-[3-(4-Allyloxy-phenyl)-3-methyl-2-oxo-pyrrolidin...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCC=C)cc1)C(=O)NO Show InChI InChI=1S/C17H22N2O4/c1-4-11-23-14-7-5-13(6-8-14)17(3)9-10-19(16(17)21)12(2)15(20)18-22/h4-8,12,22H,1,9-11H2,2-3H3,(H,18,20)/t12-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	335	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity towards Matrix metalloprotease-1 (MMP-1)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig))	BDBM50120685 (2-[3-(4-Allyloxy-phenyl)-3-methyl-2-oxo-pyrrolidin...) Show SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCC=C)cc1)C(=O)NO Show InChI InChI=1S/C17H22N2O4/c1-4-11-23-14-7-5-13(6-8-14)17(3)9-10-19(16(17)21)12(2)15(20)18-22/h4-8,12,22H,1,9-11H2,2-3H3,(H,18,20)/t12-,17+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Affinity for Tumor necrosis factor alpha converting enzyme (TACE)				J Med Chem 45: 4954-7 (2002) BindingDB Entry DOI: 10.7270/Q2XP7497
					More data for this Ligand-Target Pair