BDBM50122716 5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahydro-benzo[h][1,6]naphthyridine::CHEMBL35226

SMILES: CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1

InChI Key: InChIKey=UTMXFLLOSBJGIE-UHFFFAOYSA-N

Data: 1 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50122716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HTR4 (GUINEA PIG)	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from 5-hydroxytryptamine 4 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]mesulergine from 5-hydroxytryptamine 2C receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
Dopamine D1 receptor (Mus musculus (Mouse))	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]SCH-23390 from Dopamine receptor D1				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]5-HT from 5-hydroxytryptamine 2B receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
Vasopressin receptor (RAT)	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]AVP from vasopressin V1 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5HT1A) (Mus musculus (Mouse))	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Sus scrofa)	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]AVP from Vasopressin V2 receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]YM-0915 from Dopamine receptor D2				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]-ketanserin from 5-hydroxytryptamine 2A receptor				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM50122716 (5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahy...) Show SMILES CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 Show InChI InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Ability to displace [3H]GR-113808 from mouse 5-hydroxytryptamine 4 receptor in COS7 cells				J Med Chem 46: 138-47 (2002) Article DOI: 10.1021/jm020954v BindingDB Entry DOI: 10.7270/Q2J67G8P
					More data for this Ligand-Target Pair