BDBM50124201 5-(3-Benzyloxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127691

SMILES: O=c1[nH]cc(Cc2cccc(OCc3ccccc3)c2)c(=O)[nH]1

InChI Key: InChIKey=ZJQDPXONNQFKKC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydropyrimidine dehydrogenase [NADP(+)] (Homo sapiens (Human))	BDBM50124201 (5-(3-Benzyloxy-benzyl)-1H-pyrimidine-2,4-dione | C...) Show SMILES O=c1[nH]cc(Cc2cccc(OCc3ccccc3)c2)c(=O)[nH]1 Show InChI InChI=1S/C18H16N2O3/c21-17-15(11-19-18(22)20-17)9-14-7-4-8-16(10-14)23-12-13-5-2-1-3-6-13/h1-8,10-11H,9,12H2,(H2,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)				Bioorg Med Chem Lett 13: 867-72 (2003) BindingDB Entry DOI: 10.7270/Q21V5DBW
					More data for this Ligand-Target Pair