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SMILES: C=Cc1c[nH]c(=O)[nH]c1=O

InChI Key: InChIKey=ZRYZBEQILKESAW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124204   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydropyrimidine dehydrogenase [NADP(+)]


(Homo sapiens (Human))		BDBM50124204
PNG
(5-Vinyl-1H-pyrimidine-2,4-dione | CHEMBL170188)
Show SMILES C=Cc1c[nH]c(=O)[nH]c1=O
Show InChI InChI=1S/C6H6N2O2/c1-2-4-3-7-6(10)8-5(4)9/h2-3H,1H2,(H2,7,8,9,10)
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MMDB

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PubMed
n/an/a 89n/an/an/an/an/an/a



Nippon Roche Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)

Bioorg Med Chem Lett 13: 867-72 (2003)


BindingDB Entry DOI: 10.7270/Q21V5DBW
More data for this
Ligand-Target Pair