Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dihydropyrimidine dehydrogenase [NADP(+)]' and Ligand = 'BDBM50124204'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydropyrimidine dehydrogenase [NADP(+)] (Homo sapiens (Human))	BDBM50124204 (5-Vinyl-1H-pyrimidine-2,4-dione | CHEMBL170188) Show SMILES C=Cc1c[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C6H6N2O2/c1-2-4-3-7-6(10)8-5(4)9/h2-3H,1H2,(H2,7,8,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)				Bioorg Med Chem Lett 13: 867-72 (2003) BindingDB Entry DOI: 10.7270/Q21V5DBW
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