BindingDB PrimarySearch

null

SMILES: COc1cc(cc(OC)c1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)c2cc3OCOc3cc12

InChI Key: InChIKey=VJJPUSNTGOMMGY-MRVIYFEKSA-N

PDB links: 13 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 57 hits for monomerid = 50127140
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier organic anion transporter family member 1B3 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£tsmedizin G£ttingen Curated by ChEMBL					Assay Description Inhibition of human OATP1B3-mediated [3H]CCK-8 after 5 mins by Dixon plot method				Eur J Med Chem 92: 723-31 (2015) Article DOI: 10.1016/j.ejmech.2015.01.011 BindingDB Entry DOI: 10.7270/Q2PV6N3X
Universit£tsmedizin G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.31E+5	n/a	2.26E+5	n/a	n/a	n/a	n/a	10.5	n/a
Ahi Evran University					Assay Description Paraoxonase enzyme activity was determined at 25 �C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ...				Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ
Ahi Evran University					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.76E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Taxol transepithelial transport (basal to apical) in Caco-2 cells				Pharm Res 18: 171-6 (2001) Article DOI: 10.1023/a:1011076217118 BindingDB Entry DOI: 10.7270/Q2N300T9
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	7.56E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Vinblastine transepithelial transport (basal to apical) in MRP2-expressing MDCK cells				Pharm Res 19: 773-9 (2002) BindingDB Entry DOI: 10.7270/Q2765GMM
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	7.68E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Kansas Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) in MDR1-expressing MDCK cells				Pharm Res 19: 765-72 (2002) BindingDB Entry DOI: 10.7270/Q2BZ67B1
The University of Kansas Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	7.8	37
Medical University					Assay Description Supercoiled pHOT1 DNA (0.5 μg) was incubated with four units of human topoisomerase I in relaxation buffer (10mM Tris-HCl (pH 7.8), 1mM EDTA, 0.15...				J Enzyme Inhib Med Chem 29: 243-8 (2014) Article DOI: 10.3109/14756366.2013.768987 BindingDB Entry DOI: 10.7270/Q2416W07
Medical University					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	7.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Osaka University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 2alpha				J Nat Prod 65: 1657-9 (2002) BindingDB Entry DOI: 10.7270/Q25D8RMH
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetry				Bioorg Med Chem Lett 24: 5762-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.042 BindingDB Entry DOI: 10.7270/Q24Q7WMK
National Institute of Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Solute carrier organic anion transporter family member 1B3 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£tsmedizin G£ttingen Curated by ChEMBL					Assay Description Inhibition of human OATP1B3-mediated [3H]CCK-8 after 5 mins by Dixon plot method				Eur J Med Chem 92: 723-31 (2015) Article DOI: 10.1016/j.ejmech.2015.01.011 BindingDB Entry DOI: 10.7270/Q2PV6N3X
Universit£tsmedizin G£ttingen Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2 alpha assessed as reduction in enzyme-mediated kinetoplast DNA decatenation incubated for 30 mins by ethidium bro...				Bioorg Med Chem 23: 5654-61 (2015) Article DOI: 10.1016/j.bmc.2015.07.020 BindingDB Entry DOI: 10.7270/Q2XK8HBK
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Regulatory protein E2 (Human papillomavirus type 1a)	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a
Tokyo University of Science Curated by ChEMBL					Assay Description Binding affinity to HPV1a recombinant E2 protein by surface plasmon resonance method				Bioorg Med Chem 16: 5815-25 (2008) Article DOI: 10.1016/j.bmc.2008.03.053 BindingDB Entry DOI: 10.7270/Q24B3136
Tokyo University of Science Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresis				Eur J Med Chem 46: 3339-47 (2011) Article DOI: 10.1016/j.ejmech.2011.04.059 BindingDB Entry DOI: 10.7270/Q2513ZJD
Sun Yat-sen University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article	n/a	n/a	n/a	n/a	>7.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of calf thymus DNA/ethidium bromide complex formation.				Bioorg Med Chem Lett 5: 405-410 (1995) Article DOI: 10.1016/0960-894X(95)00044-T BindingDB Entry DOI: 10.7270/Q2CZ37N7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Integrase (Human immunodeficiency virus 1)	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Roma"La Sapienza" Curated by ChEMBL					Assay Description Compound concentration required to reduce HIV-1 Integrase 3'-processing activity by 50%				J Med Chem 41: 3948-60 (1998) Article DOI: 10.1021/jm9707232 BindingDB Entry DOI: 10.7270/Q29024G3
Universit£ di Roma"La Sapienza" Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					Assay Description Inhibition of human cytochrome P450 3A4				J Med Chem 46: 1716-25 (2003) Article DOI: 10.1021/jm021012t BindingDB Entry DOI: 10.7270/Q2ZS2X8R
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					Assay Description Inhibition of P-glycoprotein using calcein-AM assay transfected in porcine PBCEC				J Med Chem 46: 1716-25 (2003) Article DOI: 10.1021/jm021012t BindingDB Entry DOI: 10.7270/Q2ZS2X8R
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus)	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					Assay Description Inhibition of P-glycoprotein, mouse L-mdr1b expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay				J Med Chem 46: 1716-25 (2003) Article DOI: 10.1021/jm021012t BindingDB Entry DOI: 10.7270/Q2ZS2X8R
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mus musculus (Mouse))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					Assay Description Inhibition of P-glycoprotein, mouse L-mdr1a expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay				J Med Chem 46: 1716-25 (2003) Article DOI: 10.1021/jm021012t BindingDB Entry DOI: 10.7270/Q2ZS2X8R
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					Assay Description Inhibition of P-glycoprotein, human L-MDR1 expressed in LLC-PK1 epithelial cells using calcein-AM polarisation assay				J Med Chem 46: 1716-25 (2003) Article DOI: 10.1021/jm021012t BindingDB Entry DOI: 10.7270/Q2ZS2X8R
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Osaka University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor...				J Nat Prod 64: 1545-7 (2001) BindingDB Entry DOI: 10.7270/Q2X92C63
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	9.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human recombinant topoisomerase 2 by decatenation assay				Bioorg Med Chem 16: 4545-50 (2008) Article DOI: 10.1016/j.bmc.2008.02.049 BindingDB Entry DOI: 10.7270/Q20Z745T
Ewha Womans University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human recombinant DNA topoisomerase1				J Nat Prod 68: 848-52 (2005) Article DOI: 10.1021/np058007n BindingDB Entry DOI: 10.7270/Q2PK0H1B
Kobe Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manitoba Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 2alpha-mediated decatenation of kinetoplast plasmid DNA by fluorescent plate reader				Bioorg Med Chem 18: 830-8 (2010) Article DOI: 10.1016/j.bmc.2009.11.048 BindingDB Entry DOI: 10.7270/Q2KH0P8X
University of Manitoba Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Calcein-AM efflux in MDR1-expressing LLC-PK1 cells				J Med Chem 46: 1716-25 (2003) Article DOI: 10.1021/jm021012t BindingDB Entry DOI: 10.7270/Q2ZS2X8R
F. Hoffmann-LaRoche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against HeLa cell Topoisomerase II				Citation and Details BindingDB Entry DOI: 10.7270/Q2TX3HJW
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Drug concentration needed to produce a 50% reduction of bovine brain tubulin polymerization relative to the control				J Med Chem 36: 1689-99 (1993) BindingDB Entry DOI: 10.7270/Q2TB194D
Taiho Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of topoisomerase 2				Bioorg Med Chem Lett 22: 3122-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.061 BindingDB Entry DOI: 10.7270/Q2SF2X5D
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.				Citation and Details BindingDB Entry DOI: 10.7270/Q2R49SXV
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation method				Bioorg Med Chem Lett 5: 405-410 (1995) Article DOI: 10.1016/0960-894X(95)00044-T BindingDB Entry DOI: 10.7270/Q2CZ37N7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assay				J Med Chem 36: 2801-9 (1993) Article DOI: 10.1021/jm00071a010 BindingDB Entry DOI: 10.7270/Q2NK3H89
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
TBA					Assay Description Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation method				Citation and Details BindingDB Entry DOI: 10.7270/Q21R6SNT
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Bile salt export pump (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...				Toxicol Sci 118: 485-500 (2010) Article DOI: 10.1093/toxsci/kfq269 BindingDB Entry DOI: 10.7270/Q26Q20JN
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...				Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...				Toxicol Sci 136: 216-41 (2013) Article DOI: 10.1093/toxsci/kft176 BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2alpha expressed in baculovirus-infected insect cells assessed as reduction in pBR322 supercoiled DNA relaxation af...				J Med Chem 61: 1375-1379 (2018) Article DOI: 10.1021/acs.jmedchem.7b01388 BindingDB Entry DOI: 10.7270/Q2B56N5T
Istituto Italiano di Tecnologia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. Curated by ChEMBL					Assay Description Inhibition of recombinant human DNA topoisomerase-2alpha assessed as decrease in relaxation of supercoiled pBR322 DNA after 30 mins by ethidium bromi...				Bioorg Med Chem 25: 4133-4144 (2017) Article DOI: 10.1016/j.bmc.2017.06.001 BindingDB Entry DOI: 10.7270/Q2D79DWS
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Port Said University Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 2beta after 2 hrs by ELISA				Eur J Med Chem 156: 563-579 (2018) Article DOI: 10.1016/j.ejmech.2018.07.003 BindingDB Entry DOI: 10.7270/Q20G3NPD
Port Said University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2B after 2 hrs by ELISA				Eur J Med Chem 150: 403-418 (2018) Article DOI: 10.1016/j.ejmech.2018.03.026 BindingDB Entry DOI: 10.7270/Q2MS3WCZ
Cairo University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kindai University Curated by ChEMBL					Assay Description Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...				Bioorg Med Chem 26: 1920-1928 (2018) Article DOI: 10.1016/j.bmc.2018.02.042 BindingDB Entry DOI: 10.7270/Q2RR21WV
Kindai University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description In vitro activity against mammalian topoisomerase II measured as ATP-dependent unknotting of P4 DNA compared to enzyme and DNA control				J Med Chem 41: 1956-61 (1998) Article DOI: 10.1021/jm980007f BindingDB Entry DOI: 10.7270/Q2H997Z7
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Osaka University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibitory concentration against human DNA topoisomerase II				Bioorg Med Chem Lett 15: 2966-9 (2005) Article DOI: 10.1016/j.bmcl.2005.04.052 BindingDB Entry DOI: 10.7270/Q2NZ8BDQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a
UMR 176 CNRS/Institut Curie Curated by ChEMBL					Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II				J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB
UMR 176 CNRS/Institut Curie Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory activity in a DNA cleavage assay using HeLa DNA topoisomerase II yielding its effective concentration				J Med Chem 45: 5564-75 (2002) Article DOI: 10.1021/jm010057b BindingDB Entry DOI: 10.7270/Q2XS5Z46
Dainippon Pharmaceutical Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibition of human topoisomerase-2alpha using kDNA as substrate assessed as inhibition of ATP-dependent kDNA decatenation after 30 mins by agarose g...				Bioorg Med Chem 21: 5782-93 (2013) Article DOI: 10.1016/j.bmc.2013.07.016 BindingDB Entry DOI: 10.7270/Q2154M0M
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresis				Eur J Med Chem 69: 139-45 (2013) Article DOI: 10.1016/j.ejmech.2013.07.048 BindingDB Entry DOI: 10.7270/Q2JS9TCS
Ewha Womans University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of human topo2alpha incubated for 30 mins by SYBR safe DNA stain based decatenation assay				J Med Chem 63: 3508-3521 (2020) Article DOI: 10.1021/acs.jmedchem.9b01760 BindingDB Entry DOI: 10.7270/Q2251NHX
Istituto Italiano di Tecnologia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of recombinant human topoisomerase 2alpha using supercoiled pNO1 plasmid as substrate after 30 mins by SYBR-GOLD staining based fluorimetr...				J Med Chem 61: 8947-8980 (2018) Article DOI: 10.1021/acs.jmedchem.7b01202 BindingDB Entry DOI: 10.7270/Q2H998M5
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50127140 ((-)-etoposide \| (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human topoisomerase 2alpha using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based microplate reade...				Citation and Details Article DOI: 10.1039/c9md00597h BindingDB Entry DOI: 10.7270/Q29S1VQG
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)

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