BDBM50128015 1-(2,6-Difluoro-benzyl)-3-{2-[2-(1H-imidazol-4-yl)-ethylamino]-ethyl}-5-(3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione::CHEMBL64066

SMILES: COc1cccc(c1)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(CCNCCc2cnc[nH]2)c1=O

InChI Key: InChIKey=UJGDEYFNWTXRGV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50128015 (1-(2,6-Difluoro-benzyl)-3-{2-[2-(1H-imidazol-4-yl)...) Show SMILES COc1cccc(c1)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(CCNCCc2cnc[nH]2)c1=O Show InChI InChI=1S/C26H27F2N5O3/c1-17-24(18-5-3-6-20(13-18)36-2)25(34)32(12-11-29-10-9-19-14-30-16-31-19)26(35)33(17)15-21-22(27)7-4-8-23(21)28/h3-8,13-14,16,29H,9-12,15H2,1-2H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity was determined towards human gonadotropin-releasing hormone receptor				J Med Chem 46: 2023-6 (2003) Article DOI: 10.1021/jm034041s BindingDB Entry DOI: 10.7270/Q20864QQ
					More data for this Ligand-Target Pair