BDBM50133351 CHEMBL177685

SMILES: COc1cc2C(=O)C(=O)C3=C(OC(C)(C)CC3)c2cc1OC

InChI Key: InChIKey=AHYLLBLHUFMUFC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50133351 (CHEMBL177685) Show SMILES COc1cc2C(=O)C(=O)C3=C(OC(C)(C)CC3)c2cc1OC |t:9| Show InChI InChI=1S/C17H18O5/c1-17(2)6-5-9-14(18)15(19)10-7-12(20-3)13(21-4)8-11(10)16(9)22-17/h7-8H,5-6H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Basic Science (IBS) Curated by ChEMBL					Assay Description Inhibition of His-tagged human MALT1 (catalytic domain-339-719 aa) by fluorescence based assay using 25 uM Ac-LRSR-AMC as substrate				J Med Chem 58: 8491-502 (2015) BindingDB Entry DOI: 10.7270/Q2PZ5BN1
					More data for this Ligand-Target Pair