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BDBM50133352 CHEMBL3632808

SMILES: COc1ccc2C(=O)C(=O)C3=C(OC(C)(C)CC3)c2c1

InChI Key: InChIKey=BTJBWGKHSDVJEM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133352   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MALT lymphoma-associated translocation (MALT1)


(Homo sapiens (Human))		BDBM50133352
PNG
(CHEMBL3632808)
Show SMILES COc1ccc2C(=O)C(=O)C3=C(OC(C)(C)CC3)c2c1 |t:10|
Show InChI InChI=1S/C16H16O4/c1-16(2)7-6-11-14(18)13(17)10-5-4-9(19-3)8-12(10)15(11)20-16/h4-5,8H,6-7H2,1-3H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 9.20E+3n/an/an/an/an/an/a



Institute of Basic Science (IBS)

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human MALT1 (catalytic domain-339-719 aa) by fluorescence based assay using 25 uM Ac-LRSR-AMC as substrate

J Med Chem 58: 8491-502 (2015)


BindingDB Entry DOI: 10.7270/Q2PZ5BN1
More data for this
Ligand-Target Pair