BDBM50136798 CHEMBL410372::Somatostatin analogue

SMILES: C[C@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1

InChI Key: InChIKey=LWKOEELVPGZRCE-HSUQGJCQSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50136798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM50136798 (CHEMBL410372 | Somatostatin analogue) Show SMILES C[C@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C63H75N11O12S2/c1-37(75)54-62(84)71-50(32-40-19-9-4-10-20-40)59(81)73-53(63(85)86)36-88-87-35-52(72-55(77)45(65)29-41-24-26-43(76)27-25-41)61(83)69-49(31-39-17-7-3-8-18-39)57(79)68-48(30-38-15-5-2-6-16-38)58(80)70-51(33-42-34-66-46-22-12-11-21-44(42)46)60(82)67-47(56(78)74-54)23-13-14-28-64/h2-12,15-22,24-27,34,37,45,47-54,66,75-76H,13-14,23,28-33,35-36,64-65H2,1H3,(H,67,82)(H,68,79)(H,69,83)(H,70,80)(H,71,84)(H,72,77)(H,73,81)(H,74,78)(H,85,86)/t37-,45+,47-,48-,49+,50-,51+,52+,53-,54-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 1 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50136798 (CHEMBL410372 | Somatostatin analogue) Show SMILES C[C@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C63H75N11O12S2/c1-37(75)54-62(84)71-50(32-40-19-9-4-10-20-40)59(81)73-53(63(85)86)36-88-87-35-52(72-55(77)45(65)29-41-24-26-43(76)27-25-41)61(83)69-49(31-39-17-7-3-8-18-39)57(79)68-48(30-38-15-5-2-6-16-38)58(80)70-51(33-42-34-66-46-22-12-11-21-44(42)46)60(82)67-47(56(78)74-54)23-13-14-28-64/h2-12,15-22,24-27,34,37,45,47-54,66,75-76H,13-14,23,28-33,35-36,64-65H2,1H3,(H,67,82)(H,68,79)(H,69,83)(H,70,80)(H,71,84)(H,72,77)(H,73,81)(H,74,78)(H,85,86)/t37-,45+,47-,48-,49+,50-,51+,52+,53-,54-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 3 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50136798 (CHEMBL410372 | Somatostatin analogue) Show SMILES C[C@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C63H75N11O12S2/c1-37(75)54-62(84)71-50(32-40-19-9-4-10-20-40)59(81)73-53(63(85)86)36-88-87-35-52(72-55(77)45(65)29-41-24-26-43(76)27-25-41)61(83)69-49(31-39-17-7-3-8-18-39)57(79)68-48(30-38-15-5-2-6-16-38)58(80)70-51(33-42-34-66-46-22-12-11-21-44(42)46)60(82)67-47(56(78)74-54)23-13-14-28-64/h2-12,15-22,24-27,34,37,45,47-54,66,75-76H,13-14,23,28-33,35-36,64-65H2,1H3,(H,67,82)(H,68,79)(H,69,83)(H,70,80)(H,71,84)(H,72,77)(H,73,81)(H,74,78)(H,85,86)/t37-,45+,47-,48-,49+,50-,51+,52+,53-,54-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 4 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50136798 (CHEMBL410372 | Somatostatin analogue) Show SMILES C[C@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C63H75N11O12S2/c1-37(75)54-62(84)71-50(32-40-19-9-4-10-20-40)59(81)73-53(63(85)86)36-88-87-35-52(72-55(77)45(65)29-41-24-26-43(76)27-25-41)61(83)69-49(31-39-17-7-3-8-18-39)57(79)68-48(30-38-15-5-2-6-16-38)58(80)70-51(33-42-34-66-46-22-12-11-21-44(42)46)60(82)67-47(56(78)74-54)23-13-14-28-64/h2-12,15-22,24-27,34,37,45,47-54,66,75-76H,13-14,23,28-33,35-36,64-65H2,1H3,(H,67,82)(H,68,79)(H,69,83)(H,70,80)(H,71,84)(H,72,77)(H,73,81)(H,74,78)(H,85,86)/t37-,45+,47-,48-,49+,50-,51+,52+,53-,54-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 5 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50136798 (CHEMBL410372 | Somatostatin analogue) Show SMILES C[C@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C63H75N11O12S2/c1-37(75)54-62(84)71-50(32-40-19-9-4-10-20-40)59(81)73-53(63(85)86)36-88-87-35-52(72-55(77)45(65)29-41-24-26-43(76)27-25-41)61(83)69-49(31-39-17-7-3-8-18-39)57(79)68-48(30-38-15-5-2-6-16-38)58(80)70-51(33-42-34-66-46-22-12-11-21-44(42)46)60(82)67-47(56(78)74-54)23-13-14-28-64/h2-12,15-22,24-27,34,37,45,47-54,66,75-76H,13-14,23,28-33,35-36,64-65H2,1H3,(H,67,82)(H,68,79)(H,69,83)(H,70,80)(H,71,84)(H,72,77)(H,73,81)(H,74,78)(H,85,86)/t37-,45+,47-,48-,49+,50-,51+,52+,53-,54-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 2 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair