BDBM50146165 CHEMBL3764474

SMILES: Cn1ccnc1-c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2s1

InChI Key: InChIKey=ZMZOKLZTXMCMNW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50146165 (CHEMBL3764474) Show SMILES Cn1ccnc1-c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2s1 Show InChI InChI=1S/C26H20FN5O2S2/c1-32-12-11-28-24(32)22-15-18-20(9-10-29-25(18)36-22)34-21-8-7-17(14-19(21)27)30-26(35)31-23(33)13-16-5-3-2-4-6-16/h2-12,14-15H,13H2,1H3,(H2,30,31,33,35)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) by tumor cell growth inhibition assay				Eur J Med Chem 108: 495-504 (2016) BindingDB Entry DOI: 10.7270/Q2G73GMC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50146165 (CHEMBL3764474) Show SMILES Cn1ccnc1-c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2s1 Show InChI InChI=1S/C26H20FN5O2S2/c1-32-12-11-28-24(32)22-15-18-20(9-10-29-25(18)36-22)34-21-8-7-17(14-19(21)27)30-26(35)31-23(33)13-16-5-3-2-4-6-16/h2-12,14-15H,13H2,1H3,(H2,30,31,33,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of VEGFR-3 (unknown origin) by tumor cell growth inhibition assay				Eur J Med Chem 108: 495-504 (2016) BindingDB Entry DOI: 10.7270/Q2G73GMC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50146165 (CHEMBL3764474) Show SMILES Cn1ccnc1-c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2s1 Show InChI InChI=1S/C26H20FN5O2S2/c1-32-12-11-28-24(32)22-15-18-20(9-10-29-25(18)36-22)34-21-8-7-17(14-19(21)27)30-26(35)31-23(33)13-16-5-3-2-4-6-16/h2-12,14-15H,13H2,1H3,(H2,30,31,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) by tumor cell growth inhibition assay				Eur J Med Chem 108: 495-504 (2016) BindingDB Entry DOI: 10.7270/Q2G73GMC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50146165 (CHEMBL3764474) Show SMILES Cn1ccnc1-c1cc2c(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)ccnc2s1 Show InChI InChI=1S/C26H20FN5O2S2/c1-32-12-11-28-24(32)22-15-18-20(9-10-29-25(18)36-22)34-21-8-7-17(14-19(21)27)30-26(35)31-23(33)13-16-5-3-2-4-6-16/h2-12,14-15H,13H2,1H3,(H2,30,31,33,35)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of VEGFR-1 (unknown origin) by tumor cell growth inhibition assay				Eur J Med Chem 108: 495-504 (2016) BindingDB Entry DOI: 10.7270/Q2G73GMC
					More data for this Ligand-Target Pair