BDBM50147029 5-(3-{3-[(1-Pyridin-2-yl-cyclohexylmethyl)-carbamoyl]-2,3,4,9-tetrahydro-1H-carbazol-3-yl}-ureido)-isophthalic acid diethyl ester::CHEMBL105069

SMILES: CCOC(=O)c1cc(NC(=O)NC2(CCc3[nH]c4ccccc4c3C2)C(=O)NCC2(CCCCC2)c2ccccn2)cc(c1)C(=O)OCC

InChI Key: InChIKey=UCFBTASYEFRGCK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMBR (Homo sapiens (Human))	BDBM50147029 (5-(3-{3-[(1-Pyridin-2-yl-cyclohexylmethyl)-carbamo...) Show SMILES CCOC(=O)c1cc(NC(=O)NC2(CCc3[nH]c4ccccc4c3C2)C(=O)NCC2(CCCCC2)c2ccccn2)cc(c1)C(=O)OCC Show InChI InChI=1S/C38H43N5O6/c1-3-48-33(44)25-20-26(34(45)49-4-2)22-27(21-25)41-36(47)43-38(18-15-31-29(23-38)28-12-6-7-13-30(28)42-31)35(46)40-24-37(16-9-5-10-17-37)32-14-8-11-19-39-32/h6-8,11-14,19-22,42H,3-5,9-10,15-18,23-24H2,1-2H3,(H,40,46)(H2,41,43,47)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tularik Inc. Curated by ChEMBL					Assay Description Affinity of [125I]-[D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells				Bioorg Med Chem Lett 14: 3037-42 (2004) Article DOI: 10.1016/j.bmcl.2004.04.045 BindingDB Entry DOI: 10.7270/Q2PR7VF7
					More data for this Ligand-Target Pair