BDBM50147979 CHEMBL106951::{4-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-methyl-1-oxo-pentylamino)-acetyl]-piperidin-4-yl}-1-methyl-1H-pyrazol-3-yl)-phenoxymethyl]-phenyl}-acetic acid

SMILES: [#6]-[#6](-[#6])-[#6]-[#6@@H](\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1cc(nn1-[#6])-c1ccc(-[#8]-[#6]-c2ccc(-[#6]-[#6](-[#8])=O)cc2)c(Cl)c1Cl

InChI Key: InChIKey=RYQNKFRJJMROGZ-RUZDIDTESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147979   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50147979 (CHEMBL106951 | {4-[2,3-Dichloro-4-(5-{1-[2-((R)-2-...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@@H](\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1cc(nn1-[#6])-c1ccc(-[#8]-[#6]-c2ccc(-[#6]-[#6](-[#8])=O)cc2)c(Cl)c1Cl Show InChI InChI=1S/C33H41Cl2N7O5/c1-19(2)14-25(39-33(36)37)32(46)38-17-28(43)42-12-10-22(11-13-42)26-16-24(40-41(26)3)23-8-9-27(31(35)30(23)34)47-18-21-6-4-20(5-7-21)15-29(44)45/h4-9,16,19,22,25H,10-15,17-18H2,1-3H3,(H,38,46)(H,44,45)(H4,36,37,39)/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
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