BDBM50147984 2-Guanidino-4-methyl-pentanoic acid (2-{4-[5-(4-benzyloxy-2,3-dichloro-phenyl)-2-methyl-2H-pyrazol-3-yl]-piperidin-1-yl}-2-oxo-ethyl)-amide::CHEMBL265306

SMILES: [#6]-[#6](-[#6])-[#6]-[#6@@H](\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1cc(nn1-[#6])-c1ccc(-[#8]-[#6]-c2ccccc2)c(Cl)c1Cl

InChI Key: InChIKey=TUNBJBMWMJNIQH-XMMPIXPASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50147984 (2-Guanidino-4-methyl-pentanoic acid (2-{4-[5-(4-be...) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@@H](\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1cc(nn1-[#6])-c1ccc(-[#8]-[#6]-c2ccccc2)c(Cl)c1Cl Show InChI InChI=1S/C31H39Cl2N7O3/c1-19(2)15-24(37-31(34)35)30(42)36-17-27(41)40-13-11-21(12-14-40)25-16-23(38-39(25)3)22-9-10-26(29(33)28(22)32)43-18-20-7-5-4-6-8-20/h4-10,16,19,21,24H,11-15,17-18H2,1-3H3,(H,36,42)(H4,34,35,37)/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
					More data for this Ligand-Target Pair