BDBM50147993 2-Cyclohexyl-N-{2-[4-(2',4'-dichloro-biphenyl-3-yl)-piperidin-1-yl]-2-oxo-ethyl}-2-guanidino-acetamide::CHEMBL105518

SMILES: [#7]\[#6](-[#7])=[#7]/[#6@H](-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1cccc(c1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=GGPYGVTZDCLLHA-AREMUKBSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50147993 (2-Cyclohexyl-N-{2-[4-(2',4'-dichloro-biphenyl-3-yl...) Show SMILES [#7]\[#6](-[#7])=[#7]/[#6@H](-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1cccc(c1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C28H35Cl2N5O2/c29-22-9-10-23(24(30)16-22)21-8-4-7-20(15-21)18-11-13-35(14-12-18)25(36)17-33-27(37)26(34-28(31)32)19-5-2-1-3-6-19/h4,7-10,15-16,18-19,26H,1-3,5-6,11-14,17H2,(H,33,37)(H4,31,32,34)/t26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
					More data for this Ligand-Target Pair