BDBM50147995 (S)-2-[2-((S)-2-Guanidino-3-methyl-butyrylamino)-acetylamino]-3-(4-phenylethynyl-phenyl)-propionic acid methyl ester::CHEMBL318396

SMILES: [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)C#Cc1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](\[#7]=[#6](/[#7])-[#7])-[#6](-[#6])-[#6]

InChI Key: InChIKey=BWMBRQDEPKCRBD-GMAHTHKFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50147995 ((S)-2-[2-((S)-2-Guanidino-3-methyl-butyrylamino)-a...) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)C#Cc1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](\[#7]=[#6](/[#7])-[#7])-[#6](-[#6])-[#6] Show InChI InChI=1S/C26H31N5O4/c1-17(2)23(31-26(27)28)24(33)29-16-22(32)30-21(25(34)35-3)15-20-13-11-19(12-14-20)10-9-18-7-5-4-6-8-18/h4-8,11-14,17,21,23H,15-16H2,1-3H3,(H,29,33)(H,30,32)(H4,27,28,31)/t21-,23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of mouse interleukin-2 alpha receptor by ELISA				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
					More data for this Ligand-Target Pair