BDBM50148005 (S)-2-{2-[2-(N-Methyl-guanidino)-acetylamino]-acetylamino}-3-(4-phenylethynyl-phenyl)-propionic acid methyl ester::CHEMBL104059

SMILES: COC(=O)[C@H](Cc1ccc(cc1)C#Cc1ccccc1)NC(=O)CNC(=O)CN(C)C(N)=N

InChI Key: InChIKey=QWTPCZHSJAZMQH-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50148005 ((S)-2-{2-[2-(N-Methyl-guanidino)-acetylamino]-acet...) Show SMILES COC(=O)[C@H](Cc1ccc(cc1)C#Cc1ccccc1)NC(=O)CNC(=O)CN(C)C(N)=N Show InChI InChI=1S/C24H27N5O4/c1-29(24(25)26)16-22(31)27-15-21(30)28-20(23(32)33-2)14-19-12-10-18(11-13-19)9-8-17-6-4-3-5-7-17/h3-7,10-13,20H,14-16H2,1-2H3,(H3,25,26)(H,27,31)(H,28,30)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+6	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of mouse interleukin-2 alpha receptor by ELISA				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
					More data for this Ligand-Target Pair