BDBM50148007 (S)-2-(2-Methoxy-acetylamino)-3-(4-phenylethynyl-phenyl)-propionic acid::CHEMBL105741

SMILES: COCC(=O)N[C@@H](Cc1ccc(cc1)C#Cc1ccccc1)C(O)=O

InChI Key: InChIKey=BRZQWGMBJRTGOR-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50148007 ((S)-2-(2-Methoxy-acetylamino)-3-(4-phenylethynyl-p...) Show SMILES COCC(=O)N[C@@H](Cc1ccc(cc1)C#Cc1ccccc1)C(O)=O Show InChI InChI=1S/C20H19NO4/c1-25-14-19(22)21-18(20(23)24)13-17-11-9-16(10-12-17)8-7-15-5-3-2-4-6-15/h2-6,9-12,18H,13-14H2,1H3,(H,21,22)(H,23,24)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+6	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Interleukin-2 receptor alpha				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
					More data for this Ligand-Target Pair