BDBM50151377 CHEMBL3774890

SMILES: COc1ccc(cc1OCCCCCC(=O)NO)N(C)c1nc(C)nc2ccccc12

InChI Key: InChIKey=GOLDSRJBCFTJIA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50151377 (CHEMBL3774890) Show SMILES COc1ccc(cc1OCCCCCC(=O)NO)N(C)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C23H28N4O4/c1-16-24-19-10-7-6-9-18(19)23(25-16)27(2)17-12-13-20(30-3)21(15-17)31-14-8-4-5-11-22(28)26-29/h6-7,9-10,12-13,15,29H,4-5,8,11,14H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50151377 (CHEMBL3774890) Show SMILES COc1ccc(cc1OCCCCCC(=O)NO)N(C)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C23H28N4O4/c1-16-24-19-10-7-6-9-18(19)23(25-16)27(2)17-12-13-20(30-3)21(15-17)31-14-8-4-5-11-22(28)26-29/h6-7,9-10,12-13,15,29H,4-5,8,11,14H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50151377 (CHEMBL3774890) Show SMILES COc1ccc(cc1OCCCCCC(=O)NO)N(C)c1nc(C)nc2ccccc12 Show InChI InChI=1S/C23H28N4O4/c1-16-24-19-10-7-6-9-18(19)23(25-16)27(2)17-12-13-20(30-3)21(15-17)31-14-8-4-5-11-22(28)26-29/h6-7,9-10,12-13,15,29H,4-5,8,11,14H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1455-70 (2016) BindingDB Entry DOI: 10.7270/Q2T155H3
					More data for this Ligand-Target Pair