BDBM50152680 CHEMBL3780566

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4c(Cl)c5ccccc5n(-c5ccccc5)c4=O)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key: InChIKey=BKMYJTORXVRSOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50152680 (CHEMBL3780566) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(Cl)c5ccccc5n(-c5ccccc5)c4=O)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C40H36ClFN4O5/c1-49-35-24-29-31(25-36(35)50-22-10-21-45-19-8-3-9-20-45)43-18-17-33(29)51-34-16-15-26(23-30(34)42)44-39(47)37-38(41)28-13-6-7-14-32(28)46(40(37)48)27-11-4-2-5-12-27/h2,4-7,11-18,23-25H,3,8-10,19-22H2,1H3,(H,44,47)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science and Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 26: 1794-8 (2016) BindingDB Entry DOI: 10.7270/Q2TT4ST4
					More data for this Ligand-Target Pair