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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50152680'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50152680
PNG
(CHEMBL3780566)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(Cl)c5ccccc5n(-c5ccccc5)c4=O)cc3F)ccnc2cc1OCCCN1CCCCC1
Show InChI InChI=1S/C40H36ClFN4O5/c1-49-35-24-29-31(25-36(35)50-22-10-21-45-19-8-3-9-20-45)43-18-17-33(29)51-34-16-15-26(23-30(34)42)44-39(47)37-38(41)28-13-6-7-14-32(28)46(40(37)48)27-11-4-2-5-12-27/h2,4-7,11-18,23-25H,3,8-10,19-22H2,1H3,(H,44,47)
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Similars
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Jiangxi Science and Technology Normal University

Curated by ChEMBL


Assay Description
Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem Lett 26: 1794-8 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.037
BindingDB Entry DOI: 10.7270/Q2TT4ST4
More data for this
Ligand-Target Pair