BindingDB PrimarySearch

BDBM50160807 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridine::AD-5423::Blonanserin::CHEMBL178803

SMILES: CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1

InChI Key: InChIKey=XVGOZDAJGBALKS-UHFFFAOYSA-N

Data: 14 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50160807
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description In vitro binding affinity of the compound against recombinant human dopamine receptor D2L in human liver microsomes				Bioorg Med Chem Lett 15: 1055-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.028 BindingDB Entry DOI: 10.7270/Q2Z60NKV
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description In vitro binding affinity against recombinant human 5-hydroxytryptamine 2A receptor in human liver microsomes				Bioorg Med Chem Lett 15: 1055-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.028 BindingDB Entry DOI: 10.7270/Q2Z60NKV
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	14.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	56.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	286	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	3.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	7.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rattus norvegicus)	BDBM50160807 (4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 264: 158-65 (1993) BindingDB Entry DOI: 10.7270/Q2TH8K60
					More data for this Ligand-Target Pair