BDBM50161467 CHEMBL3785560

SMILES: Oc1ccc(Cl)c2CC(CN3CCC4(CCc5ccccc45)CC3)NCc12

InChI Key: InChIKey=HBTHUUQDNVQVHD-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50161467 (CHEMBL3785560) Show SMILES Oc1ccc(Cl)c2CC(CN3CCC4(CCc5ccccc45)CC3)NCc12 Show InChI InChI=1S/C23H27ClN2O/c24-21-5-6-22(27)19-14-25-17(13-18(19)21)15-26-11-9-23(10-12-26)8-7-16-3-1-2-4-20(16)23/h1-6,17,25,27H,7-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells after 45 mins by scintillation proximity assay				Eur J Med Chem 114: 345-64 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MS3
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50161467 (CHEMBL3785560) Show SMILES Oc1ccc(Cl)c2CC(CN3CCC4(CCc5ccccc45)CC3)NCc12 Show InChI InChI=1S/C23H27ClN2O/c24-21-5-6-22(27)19-14-25-17(13-18(19)21)15-26-11-9-23(10-12-26)8-7-16-3-1-2-4-20(16)23/h1-6,17,25,27H,7-15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells after 45 mins by scintillation proximity assay				Eur J Med Chem 114: 345-64 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MS3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50161467 (CHEMBL3785560) Show SMILES Oc1ccc(Cl)c2CC(CN3CCC4(CCc5ccccc45)CC3)NCc12 Show InChI InChI=1S/C23H27ClN2O/c24-21-5-6-22(27)19-14-25-17(13-18(19)21)15-26-11-9-23(10-12-26)8-7-16-3-1-2-4-20(16)23/h1-6,17,25,27H,7-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells after 60 mins by liquid scintillation counting method				Eur J Med Chem 114: 345-64 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MS3
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50161467 (CHEMBL3785560) Show SMILES Oc1ccc(Cl)c2CC(CN3CCC4(CCc5ccccc45)CC3)NCc12 Show InChI InChI=1S/C23H27ClN2O/c24-21-5-6-22(27)19-14-25-17(13-18(19)21)15-26-11-9-23(10-12-26)8-7-16-3-1-2-4-20(16)23/h1-6,17,25,27H,7-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human NOP receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding after 1.5 hrs by s...				Eur J Med Chem 114: 345-64 (2016) BindingDB Entry DOI: 10.7270/Q2DV1MS3
					More data for this Ligand-Target Pair