null

SMILES: N[C@@H](Cn1c(=O)c(c2SCC(c3ccccc3)n2c1=O)-c1ccccc1F)c1ccccc1

InChI Key: InChIKey=IVIDZBGALXXDPN-HMTLIYDFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50161508 (6-((R)-2-Amino-2-phenyl-ethyl)-8-(2-fluoro-phenyl)...) Show SMILES N[C@@H](Cn1c(=O)c(c2SCC(c3ccccc3)n2c1=O)-c1ccccc1F)c1ccccc1 |r,wD:1.0,(-7.11,-15.38,;-7.12,-13.84,;-5.79,-13.07,;-4.45,-13.83,;-3.12,-13.06,;-3.12,-11.51,;-1.79,-13.83,;-1.79,-15.37,;-.66,-16.39,;-1.27,-17.79,;-2.79,-17.63,;-3.81,-18.77,;-5.32,-18.45,;-6.35,-19.6,;-5.87,-21.07,;-4.35,-21.38,;-3.33,-20.23,;-3.11,-16.14,;-4.45,-15.37,;-5.78,-16.15,;-.46,-13.06,;.87,-13.83,;2.2,-13.06,;2.2,-11.52,;.86,-10.75,;-.47,-11.53,;-1.81,-10.77,;-8.45,-13.08,;-8.45,-11.54,;-9.79,-10.77,;-11.12,-11.54,;-11.11,-13.09,;-9.78,-13.85,)| Show InChI InChI=1S/C26H22FN3O2S/c27-20-14-8-7-13-19(20)23-24(31)29(15-21(28)17-9-3-1-4-10-17)26(32)30-22(16-33-25(23)30)18-11-5-2-6-12-18/h1-14,21-22H,15-16,28H2/t21-,22?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity was determined against human gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 15: 1407-11 (2005) Article DOI: 10.1016/j.bmcl.2005.01.009 BindingDB Entry DOI: 10.7270/Q2T72GZK
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50161508 (6-((R)-2-Amino-2-phenyl-ethyl)-8-(2-fluoro-phenyl)...) Show SMILES N[C@@H](Cn1c(=O)c(c2SCC(c3ccccc3)n2c1=O)-c1ccccc1F)c1ccccc1 |r,wD:1.0,(-7.11,-15.38,;-7.12,-13.84,;-5.79,-13.07,;-4.45,-13.83,;-3.12,-13.06,;-3.12,-11.51,;-1.79,-13.83,;-1.79,-15.37,;-.66,-16.39,;-1.27,-17.79,;-2.79,-17.63,;-3.81,-18.77,;-5.32,-18.45,;-6.35,-19.6,;-5.87,-21.07,;-4.35,-21.38,;-3.33,-20.23,;-3.11,-16.14,;-4.45,-15.37,;-5.78,-16.15,;-.46,-13.06,;.87,-13.83,;2.2,-13.06,;2.2,-11.52,;.86,-10.75,;-.47,-11.53,;-1.81,-10.77,;-8.45,-13.08,;-8.45,-11.54,;-9.79,-10.77,;-11.12,-11.54,;-11.11,-13.09,;-9.78,-13.85,)| Show InChI InChI=1S/C26H22FN3O2S/c27-20-14-8-7-13-19(20)23-24(31)29(15-21(28)17-9-3-1-4-10-17)26(32)30-22(16-33-25(23)30)18-11-5-2-6-12-18/h1-14,21-22H,15-16,28H2/t21-,22?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity at human GnRH receptor				J Med Chem 51: 3331-48 (2008) Article DOI: 10.1021/jm701249f BindingDB Entry DOI: 10.7270/Q2KD1XQ0
					More data for this Ligand-Target Pair