BDBM50164638 2',3'-Dideoxynucleoside5'-alpha-P-Borano-beta,gamma-(difluoromethylene)triphosphates derivative::CHEMBL191316

SMILES: [BH3-]P(=O)(OCC1OC(CC1F)n1cc(C)c(=O)[nH]c1=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O

InChI Key: InChIKey=BHVNVWTXLRIXLP-UHFFFAOYSA-K

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50164638 (2',3'-Dideoxynucleoside5'-alpha-P-Borano-beta,gamm...) Show SMILES [BH3-]P(=O)(OCC1OC(CC1F)n1cc(C)c(=O)[nH]c1=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O Show InChI InChI=1S/C11H18BF3N2O11P3/c1-5-3-17(10(19)16-9(5)18)8-2-6(13)7(27-8)4-26-31(12,25)28-30(23,24)11(14,15)29(20,21)22/h3,6-8H,2,4H2,1,12H3,(H,23,24)(H,16,18,19)(H2,20,21,22)/q-1/p-3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biota, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against HIV-1 reverse transcriptase				J Med Chem 48: 2695-700 (2005) Article DOI: 10.1021/jm040101y BindingDB Entry DOI: 10.7270/Q2G73FG5
					More data for this Ligand-Target Pair