BDBM50165495 CHEMBL193903::N-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phenyl]-6-pyrazol-1-yl-nicotinamide

SMILES: O=C(Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)c1ccc(nc1)-n1cccn1

InChI Key: InChIKey=VISZZGFBPNGECS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50165495 (CHEMBL193903 | N-[3-(4-Oxo-3,4-dihydro-phthalazin-...) Show SMILES O=C(Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)c1ccc(nc1)-n1cccn1 Show InChI InChI=1S/C24H18N6O2/c31-23(17-9-10-22(25-15-17)30-12-4-11-26-30)27-18-6-3-5-16(13-18)14-21-19-7-1-2-8-20(19)24(32)29-28-21/h1-13,15H,14H2,(H,27,31)(H,29,32)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Horsham Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)				Bioorg Med Chem Lett 15: 2235-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.026 BindingDB Entry DOI: 10.7270/Q2QV3M0B
					More data for this Ligand-Target Pair