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Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50165495'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50165495
PNG
(CHEMBL193903 | N-[3-(4-Oxo-3,4-dihydro-phthalazin-...)
Show SMILES O=C(Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)c1ccc(nc1)-n1cccn1
Show InChI InChI=1S/C24H18N6O2/c31-23(17-9-10-22(25-15-17)30-12-4-11-26-30)27-18-6-3-5-16(13-18)14-21-19-7-1-2-8-20(19)24(32)29-28-21/h1-13,15H,14H2,(H,27,31)(H,29,32)
PDB
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PC cid
PC sid
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Article
PubMed
n/an/a 47n/an/an/an/an/an/a



KuDOS Horsham Ltd

Curated by ChEMBL


Assay Description
Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)

Bioorg Med Chem Lett 15: 2235-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.026
BindingDB Entry DOI: 10.7270/Q2QV3M0B
More data for this
Ligand-Target Pair