BDBM50166249 5-[4-(4-Bromo-phenoxy)-phenyl]-5-[4-(4-iodo-phenyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione::CHEMBL372914

SMILES: Brc1ccc(Oc2ccc(cc2)C2(N3CCN(CC3)c3ccc(I)cc3)C(=O)NC(=O)NC2=O)cc1

InChI Key: InChIKey=IJXPNMMIIHZGBN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166249   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50166249 (5-[4-(4-Bromo-phenoxy)-phenyl]-5-[4-(4-iodo-phenyl...) Show SMILES Brc1ccc(Oc2ccc(cc2)C2(N3CCN(CC3)c3ccc(I)cc3)C(=O)NC(=O)NC2=O)cc1 Show InChI InChI=1S/C26H22BrIN4O4/c27-18-3-11-22(12-4-18)36-21-9-1-17(2-10-21)26(23(33)29-25(35)30-24(26)34)32-15-13-31(14-16-32)20-7-5-19(28)6-8-20/h1-12H,13-16H2,(H2,29,30,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital of the Westf£lische Wilhelms-Universit£t Curated by ChEMBL					Assay Description In vitro inhibition of human Matrix metalloprotease 9				J Med Chem 48: 3400-9 (2005) Article DOI: 10.1021/jm049145x BindingDB Entry DOI: 10.7270/Q2NS0VPR
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50166249 (5-[4-(4-Bromo-phenoxy)-phenyl]-5-[4-(4-iodo-phenyl...) Show SMILES Brc1ccc(Oc2ccc(cc2)C2(N3CCN(CC3)c3ccc(I)cc3)C(=O)NC(=O)NC2=O)cc1 Show InChI InChI=1S/C26H22BrIN4O4/c27-18-3-11-22(12-4-18)36-21-9-1-17(2-10-21)26(23(33)29-25(35)30-24(26)34)32-15-13-31(14-16-32)20-7-5-19(28)6-8-20/h1-12H,13-16H2,(H2,29,30,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital of the Westf£lische Wilhelms-Universit£t Curated by ChEMBL					Assay Description In vitro inhibition of human Matrix metalloprotease 2				J Med Chem 48: 3400-9 (2005) Article DOI: 10.1021/jm049145x BindingDB Entry DOI: 10.7270/Q2NS0VPR
					More data for this Ligand-Target Pair