BDBM50167634 (Z)-3-[4-(2-Bromo-phenoxy)-phenyl]-2-(3-p-tolyl-propionylamino)-acrylic acid::CHEMBL194227

SMILES: Cc1ccc(CCC(=O)N\C(=C/c2ccc(Oc3ccccc3Br)cc2)C(O)=O)cc1

InChI Key: InChIKey=RRXXFPKQBZUTAB-JWGURIENSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50167634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50167634 ((Z)-3-[4-(2-Bromo-phenoxy)-phenyl]-2-(3-p-tolyl-pr...) Show SMILES Cc1ccc(CCC(=O)N\C(=C/c2ccc(Oc3ccccc3Br)cc2)C(O)=O)cc1 Show InChI InChI=1S/C25H22BrNO4/c1-17-6-8-18(9-7-17)12-15-24(28)27-22(25(29)30)16-19-10-13-20(14-11-19)31-23-5-3-2-4-21(23)26/h2-11,13-14,16H,12,15H2,1H3,(H,27,28)(H,29,30)/b22-16-	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B (HCV NS5B polymerase) in Hepatitis C virus				Bioorg Med Chem Lett 15: 2812-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.106 BindingDB Entry DOI: 10.7270/Q26M36C7
					More data for this Ligand-Target Pair