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BDBM50170312 1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-butoxy}-1H-benzotriazole::CHEMBL424998

SMILES: CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)nnc12

InChI Key: InChIKey=SKAZIBNTPHMTSW-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170312   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50170312
PNG
(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)nnc12
Show InChI InChI=1S/C25H33N7O2/c1-5-8-20-22(14-13-21-23(20)26-31-32(21)17-25(2,3)4)34-16-7-6-15-33-19-11-9-18(10-12-19)24-27-29-30-28-24/h9-14H,5-8,15-17H2,1-4H3,(H,27,28,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 188n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr


Bioorg Med Chem Lett 15: 4068-72 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.017
BindingDB Entry DOI: 10.7270/Q2Q52P6K
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50170312
PNG
(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)nnc12
Show InChI InChI=1S/C25H33N7O2/c1-5-8-20-22(14-13-21-23(20)26-31-32(21)17-25(2,3)4)34-16-7-6-15-33-19-11-9-18(10-12-19)24-27-29-30-28-24/h9-14H,5-8,15-17H2,1-4H3,(H,27,28,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 936n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 expressed in HEK293 cells done for 1 ...


Bioorg Med Chem Lett 15: 4068-72 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.017
BindingDB Entry DOI: 10.7270/Q2Q52P6K
More data for this
Ligand-Target Pair