new BindingDB logo
myBDB logout

BDBM50172310 (1-Benzenesulfonyl-5-methoxy-1H-indol-3-ylmethyl)-dimethyl-amine::CHEMBL372364

SMILES: COc1ccc2n(cc(CN(C)C)c2c1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=GNKMXLHOOLZFRA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50172310   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50172310
PNG
((1-Benzenesulfonyl-5-methoxy-1H-indol-3-ylmethyl)-...)
Show SMILES COc1ccc2n(cc(CN(C)C)c2c1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C18H20N2O3S/c1-19(2)12-14-13-20(18-10-9-15(23-3)11-17(14)18)24(21,22)16-7-5-4-6-8-16/h4-11,13H,12H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.5n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells


Bioorg Med Chem Lett 15: 4780-5 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.028
BindingDB Entry DOI: 10.7270/Q2RN37DD
More data for this
Ligand-Target Pair