BDBM50174271 4-(piperazin-1-yl)-1H-indole::CHEMBL200234

SMILES: C1CN(CCN1)c1cccc2[nH]ccc12

InChI Key: InChIKey=YZKSXUIOKWQABW-UHFFFAOYSA-N

Data: 2 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50174271 (4-(piperazin-1-yl)-1H-indole | CHEMBL200234) Show SMILES C1CN(CCN1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C12H15N3/c1-2-11-10(4-5-14-11)12(3-1)15-8-6-13-7-9-15/h1-5,13-14H,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to beta1 adrenergic receptor (unknown origin)				J Med Chem 56: 3444-5 (2013) Article DOI: 10.1021/jm400561w BindingDB Entry DOI: 10.7270/Q23N24RC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50174271 (4-(piperazin-1-yl)-1H-indole | CHEMBL200234) Show SMILES C1CN(CCN1)c1cccc2[nH]ccc12 Show InChI InChI=1S/C12H15N3/c1-2-11-10(4-5-14-11)12(3-1)15-8-6-13-7-9-15/h1-5,13-14H,6-9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 15: 5298-302 (2005) Article DOI: 10.1016/j.bmcl.2005.08.059 BindingDB Entry DOI: 10.7270/Q2ZW1KGZ
					More data for this Ligand-Target Pair