BDBM50175451 5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID::5-(2,5-dichlorophenyl)furan-2-carboxylic acid::CHEMBL370437

SMILES: OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl

InChI Key: InChIKey=ATAZLMGGQQLRBC-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50175451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175451 (5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID | 5-(2,5-dich...) Show SMILES OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C11H6Cl2O3/c12-6-1-2-8(13)7(5-6)9-3-4-10(16-9)11(14)15/h1-5H,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Co(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175451 (5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID | 5-(2,5-dich...) Show SMILES OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C11H6Cl2O3/c12-6-1-2-8(13)7(5-6)9-3-4-10(16-9)11(14)15/h1-5H,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Fe(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175451 (5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID | 5-(2,5-dich...) Show SMILES OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C11H6Cl2O3/c12-6-1-2-8(13)7(5-6)9-3-4-10(16-9)11(14)15/h1-5H,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	693	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Mn(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50175451 (5-(2,5-DICHLOROPHENYL)-2-FUROIC ACID | 5-(2,5-dich...) Show SMILES OC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C11H6Cl2O3/c12-6-1-2-8(13)7(5-6)9-3-4-10(16-9)11(14)15/h1-5H,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.73E+5	n/a	n/a	n/a	n/a	n/a	n/a
Graduate School of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Ni(II) form of Escherichia coli MetAP				Bioorg Med Chem Lett 15: 5386-91 (2005) Article DOI: 10.1016/j.bmcl.2005.09.019 BindingDB Entry DOI: 10.7270/Q2HH6JNV
					More data for this Ligand-Target Pair				3D Structure (crystal)