BDBM50176331 6-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-4-yl)-3,4-dihydronaphthalen-1(2H)-one oxime::CHEMBL200164

SMILES: O=NC1CCCc2cc(ccc12)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1

InChI Key: InChIKey=WBHRHMNVVRGJSX-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50176331 (6-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-4-yl)-3,4...) Show SMILES O=NC1CCCc2cc(ccc12)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1 Show InChI InChI=1S/C24H20N4O/c29-28-21-8-4-7-18-15-19(9-10-20(18)21)23-22(16-11-13-25-14-12-16)26-24(27-23)17-5-2-1-3-6-17/h1-3,5-6,9-15,21H,4,7-8H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity at bRaf kinase in fluorescent ligand displacement assay				Bioorg Med Chem Lett 16: 378-81 (2005) Article DOI: 10.1016/j.bmcl.2005.09.072 BindingDB Entry DOI: 10.7270/Q2Z038Z9
					More data for this Ligand-Target Pair