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SMILES: CC(N=O)c1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1

InChI Key: InChIKey=WOTWVUVZQBUPBN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50176339   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))		BDBM50176339
PNG
(1-(4-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-4-yl)p...)
Show SMILES CC(N=O)c1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1
Show InChI InChI=1S/C22H18N4O/c1-15(26-27)16-7-9-17(10-8-16)20-21(18-11-13-23-14-12-18)25-22(24-20)19-5-3-2-4-6-19/h2-15H,1H3,(H,24,25)
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n/an/an/a 11n/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity at bRaf kinase in fluorescent ligand displacement assay

Bioorg Med Chem Lett 16: 378-81 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.072
BindingDB Entry DOI: 10.7270/Q2Z038Z9
More data for this
Ligand-Target Pair