BDBM50176721 (S)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop-2-yn-1-ol::CHEMBL200208

SMILES: CO[C@]1(CN2CCC1CC2)C#CC(O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=WUMIJQZPHGJALC-QFIPXVFZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50176721 ((S)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...) Show SMILES CO[C@]1(CN2CCC1CC2)C#CC(O)(c1ccccc1)c1ccccc1 |wU:2.11,wD:2.1,THB:1:2:5.6:9.8,(13.97,6.29,;15.45,5.91,;15.87,4.41,;16.06,3.03,;17.59,3.69,;18.96,3.06,;18.68,4.45,;17.33,5.06,;17.4,6.69,;17.85,5.59,;14.37,4.02,;12.87,3.62,;11.38,3.22,;10.99,4.71,;11.78,1.74,;10.69,.65,;11.08,-.84,;12.57,-1.24,;13.66,-.14,;13.26,1.34,;9.89,2.83,;8.8,3.92,;7.31,3.53,;6.91,2.04,;8,.94,;9.49,1.34,)| Show InChI InChI=1S/C23H25NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-11,19,25H,12-13,16-18H2,1H3/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M3 receptor				Bioorg Med Chem Lett 16: 373-7 (2005) Article DOI: 10.1016/j.bmcl.2005.09.079 BindingDB Entry DOI: 10.7270/Q2T72J70
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50176721 ((S)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop...) Show SMILES CO[C@]1(CN2CCC1CC2)C#CC(O)(c1ccccc1)c1ccccc1 |wU:2.11,wD:2.1,THB:1:2:5.6:9.8,(13.97,6.29,;15.45,5.91,;15.87,4.41,;16.06,3.03,;17.59,3.69,;18.96,3.06,;18.68,4.45,;17.33,5.06,;17.4,6.69,;17.85,5.59,;14.37,4.02,;12.87,3.62,;11.38,3.22,;10.99,4.71,;11.78,1.74,;10.69,.65,;11.08,-.84,;12.57,-1.24,;13.66,-.14,;13.26,1.34,;9.89,2.83,;8.8,3.92,;7.31,3.53,;6.91,2.04,;8,.94,;9.49,1.34,)| Show InChI InChI=1S/C23H25NO2/c1-26-22(18-24-16-12-19(22)13-17-24)14-15-23(25,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-11,19,25H,12-13,16-18H2,1H3/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Binding affinity to human muscarinic M2 receptor				Bioorg Med Chem Lett 16: 373-7 (2005) Article DOI: 10.1016/j.bmcl.2005.09.079 BindingDB Entry DOI: 10.7270/Q2T72J70
					More data for this Ligand-Target Pair