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SMILES: Nc1nc2nc(SCc3ccccc3)nc(N)c2s1

InChI Key: InChIKey=FDNXRODGTKLOEH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177610   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50177610
PNG
(5-(benzylthio)thiazolo[4,5-d]pyrimidine-2,7-diamin...)
Show SMILES Nc1nc2nc(SCc3ccccc3)nc(N)c2s1
Show InChI InChI=1S/C12H11N5S2/c13-9-8-10(16-11(14)19-8)17-12(15-9)18-6-7-4-2-1-3-5-7/h1-5H,6H2,(H4,13,14,15,16,17)
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n/an/a 1.00E+4n/an/an/an/an/an/a



AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPA

Bioorg Med Chem Lett 16: 960-3 (2006)


Article DOI: 10.1016/j.bmcl.2005.10.091
BindingDB Entry DOI: 10.7270/Q2D79B09
More data for this
Ligand-Target Pair