BDBM50178145 (S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)-5-iodopyrimidine-2,4-dione::(S)-2-((3-(2-amino-2-carboxyethyl)-5-iodo-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)methyl)benzoic acid::CHEMBL427186

SMILES: N[C@@H](Cn1cc(I)c(=O)n(Cc2ccccc2C(O)=O)c1=O)C(O)=O

InChI Key: InChIKey=HZEJBGVIAXRMKT-NSHDSACASA-N

Data: 1 KI  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus)	BDBM50178145 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...) Show SMILES N[C@@H](Cn1cc(I)c(=O)n(Cc2ccccc2C(O)=O)c1=O)C(O)=O Show InChI InChI=1S/C15H14IN3O6/c16-10-6-18(7-11(17)14(23)24)15(25)19(12(10)20)5-8-3-1-2-4-9(8)13(21)22/h1-4,6,11H,5,7,17H2,(H,21,22)(H,23,24)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 receptor expressed in HEK293 cells				J Med Chem 48: 7867-81 (2005) Article DOI: 10.1021/jm050584l BindingDB Entry DOI: 10.7270/Q2V69KCT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50178145 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...) Show SMILES N[C@@H](Cn1cc(I)c(=O)n(Cc2ccccc2C(O)=O)c1=O)C(O)=O Show InChI InChI=1S/C15H14IN3O6/c16-10-6-18(7-11(17)14(23)24)15(25)19(12(10)20)5-8-3-1-2-4-9(8)13(21)22/h1-4,6,11H,5,7,17H2,(H,21,22)(H,23,24)/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Activity at native GLUK5 kainate receptor assessed as antagonism of kainite-induced depolarization of neonatal anaesthetised rat dorsal root fibres				J Med Chem 50: 1558-70 (2007) Article DOI: 10.1021/jm061041u BindingDB Entry DOI: 10.7270/Q2X34Z8Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50178145 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...) Show SMILES N[C@@H](Cn1cc(I)c(=O)n(Cc2ccccc2C(O)=O)c1=O)C(O)=O Show InChI InChI=1S/C15H14IN3O6/c16-10-6-18(7-11(17)14(23)24)15(25)19(12(10)20)5-8-3-1-2-4-9(8)13(21)22/h1-4,6,11H,5,7,17H2,(H,21,22)(H,23,24)/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonism on GLUK5 containing kainate induced deploarization of isolated neonatal rat dorsal root C-fibers				J Med Chem 48: 7867-81 (2005) Article DOI: 10.1021/jm050584l BindingDB Entry DOI: 10.7270/Q2V69KCT
					More data for this Ligand-Target Pair