null
SMILES: Oc1cc(cc(O)c1O)C(=O)N\N=C\c1ccc(OCc2ccc3ccccc3c2)cc1
InChI Key: InChIKey=MVBQXOONTVCICP-VULFUBBASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine kinase 1 (Homo sapiens (Human)) | BDBM50178500 (CHEMBL3815133) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of GST-tagged full length human recombinant SPHK1 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measure... | Bioorg Med Chem 24: 3218-30 (2016) Article DOI: 10.1016/j.bmc.2016.05.047 BindingDB Entry DOI: 10.7270/Q2377BN8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine kinase 2 (Homo sapiens (Human)) | BDBM50178500 (CHEMBL3815133) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of GST-tagged full length human recombinant SPHK2 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measure... | Bioorg Med Chem 24: 3218-30 (2016) Article DOI: 10.1016/j.bmc.2016.05.047 BindingDB Entry DOI: 10.7270/Q2377BN8 | |||||||||||
More data for this Ligand-Target Pair |