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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sphingosine kinase 2' and Ligand = 'BDBM50178500'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sphingosine kinase 2


(Homo sapiens (Human))		BDBM50178500
PNG
(CHEMBL3815133)
Show SMILES Oc1cc(cc(O)c1O)C(=O)N\N=C\c1ccc(OCc2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C25H20N2O5/c28-22-12-20(13-23(29)24(22)30)25(31)27-26-14-16-6-9-21(10-7-16)32-15-17-5-8-18-3-1-2-4-19(18)11-17/h1-14,28-30H,15H2,(H,27,31)/b26-14+
UniProtKB/SwissProt

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Similars
Article
PubMed
n/an/a 3.02E+4n/an/an/an/an/an/a



Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged full length human recombinant SPHK2 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measure...

Bioorg Med Chem 24: 3218-30 (2016)


Article DOI: 10.1016/j.bmc.2016.05.047
BindingDB Entry DOI: 10.7270/Q2377BN8
More data for this
Ligand-Target Pair