BindingDB PrimarySearch

BDBM50184215 2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid::CHEMBL208260

SMILES: OC(=O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c(F)cc(F)cc21

InChI Key: InChIKey=BRIAEVLTRZHLAS-UHFFFAOYSA-N

Data: 8 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50184215
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50184215 (2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahy...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to TP receptor				Bioorg Med Chem Lett 16: 3043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.062 BindingDB Entry DOI: 10.7270/Q24M944X
Merck Frosst Canada & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50184215 (2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahy...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to DP receptor				Bioorg Med Chem Lett 16: 3043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.062 BindingDB Entry DOI: 10.7270/Q24M944X
Merck Frosst Canada & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50184215 (2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to EP3 receptor				Bioorg Med Chem Lett 16: 3043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.062 BindingDB Entry DOI: 10.7270/Q24M944X
Merck Frosst Canada & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50184215 (2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahy...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to IP receptor				Bioorg Med Chem Lett 16: 3043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.062 BindingDB Entry DOI: 10.7270/Q24M944X
Merck Frosst Canada & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50184215 (2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to EP4 receptor				Bioorg Med Chem Lett 16: 3043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.062 BindingDB Entry DOI: 10.7270/Q24M944X
Merck Frosst Canada & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50184215 (2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to EP2 receptor				Bioorg Med Chem Lett 16: 3043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.062 BindingDB Entry DOI: 10.7270/Q24M944X
Merck Frosst Canada & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50184215 (2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahy...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to EP1 receptor				Bioorg Med Chem Lett 16: 3043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.062 BindingDB Entry DOI: 10.7270/Q24M944X
Merck Frosst Canada & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50184215 (2-(9-(4-chlorobenzyl)-6,8-difluoro-2,3,4,9-tetrahy...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to FP receptor				Bioorg Med Chem Lett 16: 3043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.062 BindingDB Entry DOI: 10.7270/Q24M944X
Merck Frosst Canada & Co. Curated by ChEMBL					More data for this Ligand-Target Pair