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SMILES: FC(F)(F)c1ccc(cc1)-n1[nH]c2ccc(cc2c1=O)-c1ncccc1C(F)(F)F

InChI Key: InChIKey=VGTMEUVXBNRDPP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184743   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50184743
PNG
(2-(4-(trifluoromethyl)phenyl)-5-(3-(trifluoromethy...)
Show SMILES FC(F)(F)c1ccc(cc1)-n1[nH]c2ccc(cc2c1=O)-c1ncccc1C(F)(F)F
Show InChI InChI=1S/C20H11F6N3O/c21-19(22,23)12-4-6-13(7-5-12)29-18(30)14-10-11(3-8-16(14)28-29)17-15(20(24,25)26)2-1-9-27-17/h1-10,28H
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MMDB

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n/an/a 370n/an/an/an/an/an/a



Merck Sharp & Dohme

Curated by ChEMBL


Assay Description
Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assay

Bioorg Med Chem Lett 16: 2872-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.004
BindingDB Entry DOI: 10.7270/Q2959H50
More data for this
Ligand-Target Pair