Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50184743'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50184743 (2-(4-(trifluoromethyl)phenyl)-5-(3-(trifluoromethy...) Show SMILES FC(F)(F)c1ccc(cc1)-n1[nH]c2ccc(cc2c1=O)-c1ncccc1C(F)(F)F Show InChI InChI=1S/C20H11F6N3O/c21-19(22,23)12-4-6-13(7-5-12)29-18(30)14-10-11(3-8-16(14)28-29)17-15(20(24,25)26)2-1-9-27-17/h1-10,28H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Curated by ChEMBL					Assay Description Antagonist activity against capsaicin-induced intracellular calcium ion increase in CHO cells expressing human TRPV1 in FLIPR assay				Bioorg Med Chem Lett 16: 2872-6 (2006) Article DOI: 10.1016/j.bmcl.2006.03.004 BindingDB Entry DOI: 10.7270/Q2959H50
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