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BDBM50185827 CHEMBL3823523

SMILES: C[C@H](Nc1nccc(Nc2cc([nH]n2)C2CC2)n1)c1ccc2[nH]cc(Cl)c2n1

InChI Key: InChIKey=AAMUKYFUFDUBDC-JTQLQIEISA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185827   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PAK 1


(Homo sapiens (Human))		BDBM50185827
PNG
(CHEMBL3823523)
Show SMILES C[C@H](Nc1nccc(Nc2cc([nH]n2)C2CC2)n1)c1ccc2[nH]cc(Cl)c2n1 |r|
Show InChI InChI=1S/C19H19ClN8/c1-10(13-4-5-14-18(24-13)12(20)9-22-14)23-19-21-7-6-16(26-19)25-17-8-15(27-28-17)11-2-3-11/h4-11,22H,2-3H2,1H3,(H3,21,23,25,26,27,28)/t10-/m0/s1
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
PubMed
 6n/an/an/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o...

Bioorg Med Chem Lett 26: 3518-24 (2016)


BindingDB Entry DOI: 10.7270/Q2KK9DQJ
More data for this
Ligand-Target Pair