Found 3 hits for monomerid = 50188748 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50188748
(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(CNC(=O)Nc4cccc(c4)C(F)(F)F)s3)c2)CC1 Show InChI InChI=1S/C29H29F3N6OS/c1-37-9-11-38(12-10-37)17-18-5-7-23-19(13-18)14-24-26(23)35-36-27(24)25-8-6-22(40-25)16-33-28(39)34-21-4-2-3-20(15-21)29(30,31)32/h2-8,13,15H,9-12,14,16-17H2,1H3,(H,35,36)(H2,33,34,39) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 863 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of FLT1 at 1mM ATP by HTRF assay |
Bioorg Med Chem Lett 16: 4266-71 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50188748
(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(CNC(=O)Nc4cccc(c4)C(F)(F)F)s3)c2)CC1 Show InChI InChI=1S/C29H29F3N6OS/c1-37-9-11-38(12-10-37)17-18-5-7-23-19(13-18)14-24-26(23)35-36-27(24)25-8-6-22(40-25)16-33-28(39)34-21-4-2-3-20(15-21)29(30,31)32/h2-8,13,15H,9-12,14,16-17H2,1H3,(H,35,36)(H2,33,34,39) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of KDR at 1 mM ATP by HTRF assay |
Bioorg Med Chem Lett 16: 4266-71 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50188748
(1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihy...)Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(CNC(=O)Nc4cccc(c4)C(F)(F)F)s3)c2)CC1 Show InChI InChI=1S/C29H29F3N6OS/c1-37-9-11-38(12-10-37)17-18-5-7-23-19(13-18)14-24-26(23)35-36-27(24)25-8-6-22(40-25)16-33-28(39)34-21-4-2-3-20(15-21)29(30,31)32/h2-8,13,15H,9-12,14,16-17H2,1H3,(H,35,36)(H2,33,34,39) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of cKit at 1 mM ATP by HTRF assay |
Bioorg Med Chem Lett 16: 4266-71 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.066 BindingDB Entry DOI: 10.7270/Q2NP242Q |
More data for this Ligand-Target Pair | |