BDBM50191343 CHEMBL3967184
SMILES: Fc1ccc(cc1)C1=NC2C(O1)C(=O)c1ccccc1C2=O
InChI Key: InChIKey=MPHSOOSWRQUSHA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 (Homo sapiens (Human)) | BDBM50191343 (CHEMBL3967184) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Health Center Curated by ChEMBL | Assay Description Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate preincubated for 30 mins followed by substrate addition by fluorescence-based HTS ass... | J Med Chem 59: 9321-9336 (2016) BindingDB Entry DOI: 10.7270/Q2ZC84TJ | |||||||||||
More data for this Ligand-Target Pair |