BDBM50198738 CHEMBL3985361

SMILES: C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccn1

InChI Key: InChIKey=CJQXVQQIWACPJS-NGMZNZPNSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198738 (CHEMBL3985361) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H26Cl3N5O4/c1-17(24-4-2-3-11-34-24)35-29(41)27-22-15-37(30(42)26(40)16-39)14-19(12-18-5-7-20(31)8-6-18)28(22)38(36-27)25-10-9-21(32)13-23(25)33/h2-13,17,26,39-40H,14-16H2,1H3,(H,35,41)/b19-12+/t17-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.55E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198738 (CHEMBL3985361) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H26Cl3N5O4/c1-17(24-4-2-3-11-34-24)35-29(41)27-22-15-37(30(42)26(40)16-39)14-19(12-18-5-7-20(31)8-6-18)28(22)38(36-27)25-10-9-21(32)13-23(25)33/h2-13,17,26,39-40H,14-16H2,1H3,(H,35,41)/b19-12+/t17-,26+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair